Rhof Promotes Snail1 Lactylation by Enhancing PKM2-Mediated Glycolysis to Induce Pancreatic Cancer Cell Endothelial–Mesenchymal Transition

Medicine, Oncology, Life Sciences, Biochemistry,
Pancreatic Cancer   Rhof   Endothelial–Mesenchymal Transition   Glycolysis   Snail1 Lactylation  

RhoF Promotes Snail1 Lactylation by Enhancing PKM2-Mediated Glycolysis to Induce Pancreatic Cancer Cell Endothelial–Mesenchymal Transition Academic Background Pancreatic cancer (PC) is a highly malignant tumor characterized by late diagnosis, strong invasiveness, and resistance to systemic therapy, leading to poor patient prognosis. Despite recent ...