Artificial Dynamic Structure Ensemble-Guided Rational Design of a Universal RNA Aptamer–Based Sensing Tag

Life Sciences, Biochemistry, Bioengineering, Genetics, Biophysics,
Artificial RNA   Dynamic Structure Ensemble   Fluorogenic RNA Aptamer   Biosensing   Gene Editing  

Artificial Dynamic RNA Structure Ensemble-Guided Rational Design of a Universal RNA Aptamer-Based Sensing Tag Academic Background RNA molecules play versatile roles in both natural and synthetic biological systems, with their functions strongly dependent on their dynamic and specific three-dimensional structures. RNA secondary and tertiary structur...