The Impact of Nanotopography on Cellular Metabolic Activities: Multimodal Imaging Reveals New Insights Academic Background In the field of biomedicine, the interaction between cells and material surfaces is crucial for studying cell behavior, tissue engineering, and regenerative medicine. Nanoscale surface topography (nanotopography) has been shown...
Research on the Modulation of Physical Properties of Biomaterials to Enhance Vascularization Background Introduction In the fields of tissue engineering and regenerative medicine, the formation of a vascular system and adequate blood perfusion are crucial for ensuring the supply of nutrients and oxygen within biomaterials. However, existing biomate...
Application of Electrospun Fibers in Modulating Foreign Body Response Background Introduction In the field of biomedicine, the use of implantable medical devices (such as subcutaneous implants) is becoming increasingly widespread. However, these devices often trigger an immune response in the host after implantation, known as the Foreign Body Respo...
Exosomes as Biomarkers for Precision Diagnosis of Lung Cancer Academic Background Lung cancer is one of the leading causes of cancer-related deaths worldwide, with early diagnosis and precision treatment of non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) remaining significant challenges. Although traditional tissue biopsy is co...
Applications of Volumetric Additive Manufacturing in Cell Printing Academic Background Volumetric Additive Manufacturing (VAM) is a revolutionary 3D printing technology capable of rapidly creating complex three-dimensional structures, particularly in the field of cell printing. VAM can mimic the structures of natural tissues, offering new possibili...
Advanced Bioresponsive Drug Delivery Systems for Diabetic Vascularized Bone Regeneration Background The treatment of bone defects in patients with Diabetes Mellitus (DM) remains a significant challenge, as the diabetic microenvironment severely impedes bone regeneration. Various abnormal factors in the diabetic microenvironment, such as hyperglycem...
Self-Assembled DNA-Collagen Bioactive Scaffolds Promote Cellular Uptake and Neuronal Differentiation Academic Background In molecular biology research, the interaction between DNA and proteins has always been a crucial topic for understanding cellular processes. With the deepening understanding of DNA-protein interactions, this knowledge has been w...
Magnetic Nanoplatform Based on CD26 Targeting and HSP90 Inhibition for Apoptosis and Ferroptosis-Mediated Elimination of Senescent Cells Academic Background With the intensification of population aging, the accumulation of senescent cells is considered a significant hallmark of aging and age-related diseases. Senescent cells are not only associated...
Enhancing Gene Delivery to Breast Cancer with Highly Efficient siRNA Loading and pH-Responsive Small Extracellular Vesicles Academic Background In recent years, small extracellular vesicles (sEVs) have become a hot topic in the field of drug delivery due to their natural origin and inherent homing properties. sEVs are lipid nanoparticles secreted b...
Synthesis of Palladium Nanoparticles by Electrode-Respiring Geobacter sulfurreducens Biofilms Research Background In modern industry and environmental science, palladium (Pd) serves as a crucial catalyst widely used in pharmaceuticals, agriculture, and chemical industries. However, traditional methods for synthesizing palladium nanoparticles (Pd NP...