ACImpute: A Constraint-Enhancing Smooth-Based Approach for Imputing Single-Cell RNA Sequencing Data

Single-cell RNA sequencing (scRNA-seq) technology has been widely applied in biological and medical research in recent years. It can reveal the transcriptomic information of individual cells, helping scientists better understand cellular heterogeneity and complexity. However, a common issue in scRNA-seq data is “dropout events,” which result in man...