Inotuzumab Ozogamicin and Low-Intensity Chemotherapy in Older Patients with Newly Diagnosed CD22+ Philadelphia Chromosome–Negative B-Cell Precursor Acute Lymphoblastic Leukemia

Medicine, Hematology, Oncology,
Inotuzumab Ozogamicin   Low-Intensity Chemotherapy   Acute Lymphoblastic Leukemia   Older Patients   CD22 Positive   Philadelphia Chromosome Negative   B-Cell Precursor  

Academic Background and Problem Acute lymphoblastic leukemia (ALL) is a malignant hematologic disease, particularly challenging to treat in older patients, with limited treatment options and poor outcomes. Traditional chemotherapy regimens yield long-term survival rates of only 20%-30% in elderly patients. Therefore, finding more effective and bett...