Cytosolic pH is a Direct Nexus in Linking Environmental Cues with Insulin Processing and Secretion in Pancreatic β Cells

Cytosolic pH is a Direct Nexus in Linking Environmental Cues with Insulin Processing and Secretion in Pancreatic β Cells

The Direct Link between Cytosolic pH and Environmental Signals, Insulin Processing, and Secretion in Pancreatic β Cells Background Pancreatic β cells respond to glucose fluctuations by regulating insulin processing and secretion. However, how this process is finely tuned within a complex and variable microenvironment, and whether its dysfunction is...