In modern society, sleep deficiency has become one of the major causes of metabolic diseases. Studies have shown that insufficient sleep increases energy intake, but its effects on energy expenditure remain unclear. Although some clinical research indicates that sleep-deprived populations exhibit greater energy intake, energy expenditure does not c...
Academic Background The preservation of the parathyroid glands (PGs) during thyroidectomy is crucial, as postoperative hypoparathyroidism is a common complication of thyroid surgery, particularly after total thyroidectomy. Approximately 30%-40% of patients experience transient hypoparathyroidism, with 5%-10% developing permanent hypoparathyroidism....
In recent years, the role of the gut microbiome in human health and disease has garnered significant attention. Research indicates that gut microbial dysbiosis is closely associated with various chronic diseases, such as obesity, inflammatory bowel disease, cancer, and neurodegenerative disorders. Diet, as a critical factor influencing the gut micr...
Research Background Cardiovascular diseases (CVD) are one of the leading causes of death worldwide, particularly among patients with diabetes and insulin resistance, where the risk of CVD is significantly elevated. Although the prognosis for diabetic patients has improved in recent years, their CVD-related mortality rate remains 2 to 7 times higher...
New Mechanism of Diabetic Cardiomyopathy: The Role of Fibroblast-Specific TGF-β/Smad3 Signaling Pathway Research Background Diabetes is a significant risk factor for cardiovascular diseases and heart failure (HF) globally. Diabetic patients not only face risks of macrovascular complications such as hypertension and atherosclerosis but are also pron...
Academic Background Pituitary adenomas (PAs) are common intracranial tumors with complex pathogenesis, often accompanied by abnormal hormone secretion. Although various treatments, such as dopamine agonists (DAs), are currently available, some patients exhibit drug resistance, leading to suboptimal therapeutic outcomes. Therefore, identifying new t...
Research Report on Low-Energy Diet Intervention in Gestational Diabetes Academic Background Gestational Diabetes Mellitus (GDM) is a form of diabetes diagnosed for the first time during pregnancy, with a global incidence rate of approximately 6-15%. GDM not only increases the risk of short-term complications for both mothers and fetuses, such as la...
The Impact of Circadian Rhythms and Behavioral Cycles on Caloric Intake in Adolescents Varies by Weight Status Academic Background The prevalence of obesity continues to rise globally, particularly among adolescents, increasing the risk of various chronic diseases such as type 2 diabetes, hypertension, and cardiovascular disorders. While previous s...
KATP Channels Modulate Cortical Activity and Sleep by Regulating Glycolytic Flux Academic Background Glucose serves not only as the primary energy source for the brain but also as a biosynthetic substrate for neurotransmitter synthesis. Changes in glycolytic flux can alter neurotransmitter synthesis, thereby modulating cortical electroencephalograp...
Study on Hormone-Neuropeptide Pathway Inhibiting Sexual Receptivity in Immature Drosophila Females Academic Background Sexual maturation is a critical developmental event in the transition from juvenile to adult, accompanied by multiple physiological and behavioral changes. In Drosophila, the process of transition from an asexual state to sexual ma...