Hierarchical Negative Sampling Based Graph Contrastive Learning Approach for Drug-Disease Association Prediction

Information Science, Computer Science, Artificial Intelligence, Medicine, Pharmacy, Life Sciences, Biochemistry,
Drug-Disease Association   Contrastive Learning   Graph Neural Networks   Negative Sampling   Heterogeneous Network  

Research on Drug-Disease Association Prediction Using Graph Contrastive Learning Based on Layered Negative Sampling The prediction of drug-disease associations (RDAs) plays a critical role in unveiling disease treatment strategies and promoting drug repurposing. However, existing methods mainly rely on limited domain-specific knowledge when predict...