An Electromechanical Model-Based Study on the Dosage Effects of Ranolazine in Treating Failing HCM Cardiomyocyte

Hypertrophic Cardiomyopathy (HCM) is a common inherited heart disease, affecting approximately 1 in 500 people globally. The primary characteristic of HCM is asymmetric hypertrophy of the myocardium. In its early stages, it may manifest as hyperdynamic contraction of the left ventricle (LV). However, as the disease progresses, patients may develop ...