Chronic Evoked Seizures in Young Pre-symptomatic APP/PS1 Mice Induce Serotonin Changes and Accelerate Onset of Alzheimer’s Disease-Related Neuropathology
APP/PS1 Mouse Study Reveals Link Between Chronic Induced Epilepsy and Alzheimer’s Disease Background Alzheimer’s Disease (AD) is the most common type of dementia globally, affecting over 55 million people. The typical pathological feature of AD is the deposition of amyloid-β (Aβ) in the brain. Although Aβ deposition and the mechanisms it triggers p...