Causative Study of Ehlers-Danlos Syndrome with Prominent Vascular Features

Medicine, Cardiovascular System, Life Sciences, Genetics,
Genetics   Connective Tissue Disorder   Vascular Fragility   THBS2 Gene Mutation   CRISPR/Cas9 Mouse Model  

Heterozygous THBS2 Pathogenic Variants Cause Ehlers-Danlos Syndrome with Prominent Vascular Features in Humans and Mice Paper Background Ehlers-Danlos syndrome (EDS) is a group of connective tissue disorders caused by mutations in collagen and collagen-related genes. These disorders present in various forms and can be classified into 14 different t...