Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy

This is a research report on focal cortical dysplasia (FCD) type II. The authors aim to investigate the cellular senescence phenomenon present in FCD II and whether targeting these senescent cells can alleviate seizures. Background: FCD II is a common cortical malformation causing childhood epilepsy and developmental delay. It is caused by somatic ...