Academic Background The regenerative capacity of the nervous system varies significantly between different regions. Axons in the peripheral nervous system (PNS) can regenerate spontaneously after injury, whereas axons in the central nervous system (CNS) lack this ability. This difference makes recovery after CNS injury extremely challenging, especi...
Academic Background The field of neuroscience has long been dedicated to understanding how neural circuits generate and control complex behaviors. Although simple model organisms, such as mollusks, crustaceans, and annelids, have provided valuable models for research due to their accessible nervous systems and large characteristic neurons, in many ...
S-nitrosylation of CRTC1 in Alzheimer’s Disease Impairs CREB-dependent Gene Expression Induced by Neuronal Activity Academic Background Alzheimer’s disease (AD) is a common neurodegenerative disorder characterized by the gradual loss of memory and cognitive function. The pathological mechanisms of AD are complex, involving various molecular and cel...
Radiation-Induced Cellular Plasticity Primes Glioblastoma for Forskolin-Mediated Differentiation Academic Background Glioblastoma (GBM) is one of the deadliest brain cancers in adults, with a median survival period of only 15 to 18 months for patients. Although surgery combined with chemoradiotherapy can delay disease progression, these treatments ...
The Protective Role of Parenthood on Brain Function Academic Background Parenthood is a universal stage in human life that profoundly impacts both the body and mind, and may also have long-term effects on brain function. However, current research on the long-term impact of parenthood on brain function, especially its relationship with brain aging, ...
Endocannabinoids Released on Demand via Extracellular Microvesicles Academic Background Endocannabinoids (ECBs) are a class of lipid neurotransmitters that play a critical role in brain function by activating cannabinoid receptor CB1. Unlike classical neurotransmitters, the storage and release mechanisms of ECBs have remained elusive, leading to si...
GABAergic Synapses Between Auditory Efferent Neurons and Type II Spiral Ganglion Afferent Neurons in the Mouse Cochlea Background Introduction The complexity and precision of the auditory system have always been important topics in neuroscience research. As a key component of the auditory system, the interactions between cells and neurons within th...
Brain Age Prediction Study Based on MEG Time Series Academic Background With the extension of human lifespan, understanding changes in the brain throughout the life cycle has become increasingly important. The structure and function of the brain undergo significant changes with age, which not only affect cognitive functions but are also closely rel...
KATP Channels Modulate Cortical Activity and Sleep by Regulating Glycolytic Flux Academic Background Glucose serves not only as the primary energy source for the brain but also as a biosynthetic substrate for neurotransmitter synthesis. Changes in glycolytic flux can alter neurotransmitter synthesis, thereby modulating cortical electroencephalograp...
Study on Hormone-Neuropeptide Pathway Inhibiting Sexual Receptivity in Immature Drosophila Females Academic Background Sexual maturation is a critical developmental event in the transition from juvenile to adult, accompanied by multiple physiological and behavioral changes. In Drosophila, the process of transition from an asexual state to sexual ma...