Gene × Environment Effects and Mediation Involving Adverse Childhood Events, Mood and Anxiety Disorders, and Substance Dependence

Medicine, Environmental and Public Health, Neurology,
adverse childhood events   mood disorders   anxiety disorders   substance dependence   gene-environment interaction   mediation   psychopathology  

Study on the Genetic and Environmental Effects of Adverse Childhood Events, Mood and Anxiety Disorders, and Substance Dependence I. Background and Significance Adverse childhood events (ACE) often have profound effects on an individual’s mental health and substance dependence. Previous studies have shown a close relationship between ACE and mood an...