The Relationship Between Cancer Risk and Epigenetic Age Acceleration After Stroke

Study on the Association Between Long-Term Cancer Risk and Epigenetic Age in Stroke Survivors Background and Significance Cancer and stroke are leading global causes of morbidity and mortality, with their association being increasingly recognized. Statistics show that about 6% of cancer patients experience a stroke during their lifetime, while stro...

Effectiveness of Ocrelizumab in Primary Progressive Multiple Sclerosis: A Multicenter, Retrospective Real-World Study

Effectiveness of Ocrelizumab in Primary Progressive Multiple Sclerosis: A Multicenter, Retrospective Real-World Study Background and Research Motivation Multiple sclerosis (MS) is a chronic, complex, inflammatory, and degenerative demyelinating disease primarily affecting the central nervous system (CNS). It can lead to neurological impairments in ...

Sex-Specific Association of Cardiovascular Risk Factors with Migraine: The Population-Based Rotterdam Study

Research Report on Gender-Specific Association Between Cardiovascular Risk Factors and Migraine Academic Background Migraine is a common neurological disorder. Previous studies have shown that migraine, especially migraine with aura, is associated with cardiovascular events such as myocardial infarction, coronary heart disease, and cardiovascular m...

Public Views on Whether the Use of Pharmaceutical Neuroenhancements Should Be Allowed

Research Report on Whether the Public Should Be Allowed to Use Drug Enhancers Introduction In recent years, some individuals have started using drugs to enhance cognitive and socio-emotional functions and have requested off-label prescriptions from doctors for neuroenhancement (e.g., stimulants). However, discussions about whether such uses should ...

A Vaping Cessation Text Message Program for Adolescent E-Cigarette Users: A Randomized Clinical Trial

E-cigarette Cessation SMS Program: A Randomized Clinical Trial Study Targeting Adolescent E-cigarette Users Background In recent years, e-cigarettes have become the most widely used tobacco product among American adolescents. Statistics from 2023 show that over 2.1 million adolescents reported current use of e-cigarettes, including 10% of high scho...

Associations of Internal Medicine Residency Milestone Ratings and Certification Examination Scores with Patient Outcomes

Associations of Internal Medicine Residency Milestone Ratings and Certification Examination Scores with Patient Outcomes

Association Between Milestone Ratings and Certification Exam Scores of Medical Residents and Patient Outcomes Background In the United States, the education and competency assessment of internal medicine residents are primarily conducted through two methods: the Milestone assessment system and the American Board of Internal Medicine (ABIM) certific...

Mortality and Morbidity in Adults with Rheumatic Heart Disease

Mortality and Morbidity in Adults with Rheumatic Heart Disease

Rheumatic Heart Disease Mortality Risk Factors Mortality and Incidence of Rheumatic Heart Disease in Adults Research Background Rheumatic heart disease (RHD) causes over 300,000 deaths annually, primarily in low- and middle-income countries (LMICs). Due to a lack of high-quality epidemiological data, understanding of the incidence and mortality of ...

A Scoping Review on Examination Approaches for Identifying Tactile Deficits at the Upper Extremity in Individuals with Stroke

Academic Report on “The Scope Review of Upper Limb Tactile Deficit Examination Methods” In recent years, post-stroke patients’ capacity to perceive tactile stimuli has become a focal point of research. This perception is very important for the execution of movements and learning activities in everyday life. However, tactile perceptual deficits seri...

Trend Change Analysis of Postural Balance in Parkinson’s Disease Discriminates Between Medication State

Analysis of Trend Changes in Static Balance of Parkinson’s Disease Patients to Distinguish Drug States Introduction Maintaining static body balance is crucial for daily living, which requires coordination between different body segments. Any change or decline in balance ability increases the risk of falling. Patients with Parkinson’s disease (PD) e...

Sex-dependent effects of carbohydrate source and quantity on caspase-1 activity in the mouse central nervous system

The Gender-Dependent Effects of Carbohydrate Sources and Quantity on Caspase-1 Activity in the Central Nervous System of Mice Research Background With the global intensification of aging, the incidence of cognitive impairments and dementia is rapidly increasing, with Alzheimer’s disease being the most common form of senile dementia. Studies have sh...