Tracing Carriage, Acquisition, and Transmission of ESBL-Producing Escherichia coli Over Two Years in a Tertiary Care Hospital

Report on a Study of the Dynamics of Carriage, Acquisition, and Transmission of ESBL-Producing E. coli (ESBL-EC) in Non-ICU Hospital Wards Over Two Years Antimicrobial resistance is an increasingly significant global public health issue, with the rapid dissemination of extended-spectrum beta-lactamase-producing (ESBL) Enterobacterales, such as Kleb...

Genomic Surveillance of Multidrug-Resistant Organisms Based on Long-Read Sequencing

Genomic Surveillance of Multidrug-Resistant Organisms Based on Long-Read Sequencing Research Background Multidrug-resistant organisms (MDROs) are a significant global public health threat. These organisms exhibit resistance to multiple antibiotics, making infections challenging to treat and increasing healthcare costs. To effectively monitor and co...

Trends in Screening for Social Risk in US Physician Practices

Trends in Screening for Social Risk in US Physician Practices Report Academic Background In recent years, the importance of social risk screening in healthcare has become increasingly prominent, with more research focusing on identifying patients’ social risk factors such as food insecurity, housing instability, utility needs, interpersonal violenc...

Social Risks and Nonadherence to Recommended Cancer Screening Among US Adults

The Relationship Between Social Risks and Cancer Screening Adherence Among U.S. Adults Academic Background Cancer screening is a critical tool for the early detection and prevention of cancer, significantly improving treatment outcomes and reducing mortality rates. However, despite recommendations from various U.S. health agencies for colorectal, l...

A Couple-Based Intervention for Chinese Older Adults with Type 2 Diabetes: A Randomized Clinical Trial

Report on the Management of Chinese Older Adults with Type 2 Diabetes through Couple-Based Interventions: A Randomized Clinical Trial Academic Background Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic diseases globally, particularly common among older adults. China has the largest number of diabetes patients worldwide, reachin...

Increased Emergency Department Medical Imaging: Association with Short-Term Exposures to Ambient Heat and Particulate Air Pollution

The Relationship Between Climate Change and Emergency Medical Imaging Utilization Academic Background Climate change and related environmental exposures have significantly impacted human health, leading to increased demand for healthcare services. High-temperature exposure and poor air quality are closely associated with increased emergency departm...

Toward Optimal Disease Surveillance with Graph-Based Active Learning

Toward Optimal Disease Surveillance with Graph-Based Active Learning Academic Background With the acceleration of globalization, the speed and scope of infectious disease transmission have significantly increased. How to effectively monitor and control the spread of infectious diseases has become a critical issue in public health. Traditional disea...

The Relationship Between Cancer Risk and Epigenetic Age Acceleration After Stroke

Study on the Association Between Long-Term Cancer Risk and Epigenetic Age in Stroke Survivors Background and Significance Cancer and stroke are leading global causes of morbidity and mortality, with their association being increasingly recognized. Statistics show that about 6% of cancer patients experience a stroke during their lifetime, while stro...

Effectiveness of Ocrelizumab in Primary Progressive Multiple Sclerosis: A Multicenter, Retrospective Real-World Study

Effectiveness of Ocrelizumab in Primary Progressive Multiple Sclerosis: A Multicenter, Retrospective Real-World Study Background and Research Motivation Multiple sclerosis (MS) is a chronic, complex, inflammatory, and degenerative demyelinating disease primarily affecting the central nervous system (CNS). It can lead to neurological impairments in ...

Sex-Specific Association of Cardiovascular Risk Factors with Migraine: The Population-Based Rotterdam Study

Research Report on Gender-Specific Association Between Cardiovascular Risk Factors and Migraine Academic Background Migraine is a common neurological disorder. Previous studies have shown that migraine, especially migraine with aura, is associated with cardiovascular events such as myocardial infarction, coronary heart disease, and cardiovascular m...