Sul-BERTGRU: An Ensemble Deep Learning Method Integrating Information Entropy-Enhanced BERT and Directional Multi-GRU for S-Sulfhydration Sites Prediction

Information Science, Artificial Intelligence, Life Sciences, Cell Biology, Biochemistry,
deep learning   S-sulfhydration sites   information entropy   BERT   multi-directional GRU   protein modification   bioinformatics  

Background Introduction Post-Translational Modifications (PTMs) are crucial mechanisms for regulating cellular activities, including gene transcription, DNA repair, and protein interactions. Among these, cysteine, a rare amino acid, participates in various PTMs through its thiol group, playing a significant role in redox balance and signal transduc...