Sul-BERTGRU: An Ensemble Deep Learning Method Integrating Information Entropy-Enhanced BERT and Directional Multi-GRU for S-Sulfhydration Sites Prediction

Information Science, Artificial Intelligence, Life Sciences, Cell Biology, Biochemistry,
deep learning   S-sulfhydration sites   information entropy   BERT   multi-directional GRU   protein modification   bioinformatics  

Background Introduction Post-Translational Modifications (PTMs) are crucial mechanisms for regulating cellular activities, including gene transcription, DNA repair, and protein interactions. Among these, cysteine, a rare amino acid, participates in various PTMs through its thiol group, playing a significant role in redox balance and signal transduc...

The Effect of Sodium Butyrate on Gene Expression and Protein Modification in Streptomyces

Life Sciences, Biochemistry, Genetics, Microbiology,
silent gene cluster   streptomyces   sodium butyrate   protein modification   acetylation  

Multi-omics Data Reveals the Impact of Sodium Butyrate on Gene Expression and Protein Modification in Streptomyces Academic Background Streptomyces has attracted widespread attention due to its rich gene clusters and potential for producing a large number of natural products. Histone deacetylase (HDAC) inhibitors play an important role in histone m...