GDF15 Antagonism Limits Severe Heart Failure and Prevents Cardiac Cachexia

Heart Failure (HF) is a complex disease with increasing incidence and poor prognosis. Cardiac cachexia, a common complication in HF patients, is characterized by significant weight loss, muscle wasting, and malnutrition, and its occurrence is independently associated with patient morbidity and mortality. Although cardiac cachexia is prevalent in HF...