Machine Learning and Confirmatory Factor Analysis Show that Buprenorphine Alters Motor and Anxiety-like Behaviors in Male, Female, and Obese C57BL/6J Mice

In recent years, with the global increase in drug abuse, particularly opioids, scientists have become increasingly focused on the neurobehavioral effects of such substances. Among them, buprenorphine, an opioid, is widely used for medication-assisted treatment of opioid addiction. However, beyond its analgesic and addiction treatment effects, bupre...