Spectinomycin-Loaded Antibacterial Polyvinyl Alcohol/Silver Oxide Nanobiocomposite Hydrogel: Synthesis, Characterization, Swelling, Cytotoxicity, and Controlled Drug Release Carrier

Academic Background In the field of drug delivery, achieving long-term and controlled release of drugs is a significant research direction. Hydrogels, as materials with excellent biocompatibility and degradability, have been widely used in drug delivery, tissue engineering, and wound dressing. However, the low mechanical strength of traditional hyd...

Pseudomonas fluorescens–Based Biogenic Silver Nanoparticles: A Green Solution for Brown Leaf Spot Disease in Rice

Academic Background Rice (Oryza sativa L.) is a globally important food crop, providing a primary source of calories for approximately one-fifth of the world’s population. However, rice production faces various biotic and abiotic stresses, leading to reduced yields. Among these, rice brown leaf spot disease, caused by the fungal pathogen Cochliobol...

Development and Characterization of Baricitinib Nanoemulgel with Antiarthritic Effect in Rats

Academic Background Rheumatoid Arthritis (RA) is a chronic autoimmune disease that primarily affects the synovial membrane of joints, leading to inflammation and erosive lesions. Approximately 0.5% to 1% of the global population is affected by this disease, particularly among the elderly, who often experience dysphagia, which limits the compliance ...

Synthesis and Characterization of Pyrogallol Silver Nanoparticles and Pyrogallol Nanocomposites and Their Effects on Radiation-Induced Toxicity in HEK293 Cells

Academic Background Cancer is a complex and highly prevalent disease worldwide, causing nearly 10 million deaths annually. Early diagnosis and effective treatment are crucial for improving patient survival rates. Current cancer treatment modalities include surgery, chemotherapy, radiotherapy, and immunotherapy. Among these, radiotherapy is a critic...

Arabinoxylan-Incorporated Poly(ε-Caprolactone) Nanofiber Matrix Promotes Fibroblast Cell Adhesion and Proliferation

Academic Background Wound healing is a complex physiological process involving multiple coordinated stages, including hemostasis, inflammation, proliferation, and remodeling. However, in cases of severe trauma or chronic wounds, traditional treatments such as dressings and sutures often have limited efficacy. In recent years, the development of tis...

Synthesis, Physicochemical Characterization, and Antimicrobial Evaluation of Ureasil-Polyether Coatings with Silver Nanoparticles for Hospital Devices

Research Background Nosocomial infections are a common and serious problem in healthcare settings, particularly on reusable medical devices, where cross-contamination and biofilm formation are major causes. To address this challenge, researchers have begun exploring the use of coating materials containing metallic nanoparticles to prevent microbial...

Effects of Bare and PEG Coated Gold Nanoparticles on RRM2 Protein: A Pathway Analysis and MD Simulations Approach

Academic Background Nanoparticles (NPs) have increasingly been applied in the medical field, particularly in bioimaging, biosensing, and drug delivery. Gold nanoparticles (AuNPs), due to their unique physicochemical properties, have become a focal point in biomedical research. However, despite their significant therapeutic potential, the biosafety ...

Changes in Growth and Secondary Metabolite Production in Cannabis sativa L. in Response to Simultaneous Treatment with Plasma-Activated Water, Melatonin, and Nano-Zinc

Academic Background Industrial hemp (Cannabis sativa L.) holds significant value in the pharmaceutical and industrial sectors due to its rich secondary metabolites, such as cannabinoids, terpenoids, and flavonoids. Cannabinoids, including tetrahydrocannabinol (THC) and cannabidiol (CBD), exhibit notable pharmacological activities, with THC being ps...

Eucalyptus Globulus Essential Oil-Based Nanoemulsions: Comprehensive Development, In Vitro and In Silico Assessment Against Spodoptera Litura

Academic Background With the rapid growth of the global population, which is expected to reach 9.7 billion by 2050, food security has become an increasingly pressing issue. Agricultural productivity is affected by various factors, with pest damage to crops being particularly severe. The tobacco cutworm (Spodoptera litura), a polyphagous pest widely...

Structural, Optical, and Antibacterial Properties of NiO and BaO Doped NiO Prepared by Co-Precipitation Method

Academic Background Nickel oxide (NiO), as a p-type semiconductor, has garnered significant attention due to its exceptional optical properties, chemical stability, and extensive applications in optoelectronics, photocatalysis, and biosensors. NiO’s high transparency, adjustable electrical conductivity, and wide bandgap make it an ideal material fo...