The Impairment of Deviance Detection in the Auditory Cortex by DOI Academic Background Psychedelics are a class of psychoactive substances that can significantly alter perception, cognition, and mood. In recent years, psychedelics have shown potential applications in treating conditions such as depression, anxiety, and trauma-related disorders. How...
New Discoveries in Cortical Motor Maps Background Introduction Humans and other primates are capable of performing a wide range of complex body movements, the initiation and control of which rely on multiple cortical and subcortical structures. Among these, the primary motor cortex (M1), located in the precentral gyrus, is the core region for execu...
Research Priorities for Improving Cognitive and Neuropsychological Outcomes in Hydrocephalus Academic Background Hydrocephalus is a neurological disorder affecting approximately 85 per 100,000 individuals worldwide. It is closely associated with motor and cognitive impairments. Although advancements in surgical interventions have significantly impr...
Epigenome-wide DNA Methylation Study Highlights PTSD-Associated Sites: A Meta-Analysis Across 23 Military and Civilian Cohorts Background and Research Objectives Post-Traumatic Stress Disorder (PTSD) is a serious psychiatric condition triggered by exposure to traumatic events. It is characterized by intrusive memories, avoidance or emotional numbne...
Clinical Decision Support Guided by Risk Models in Suicide Screening: A Randomized Clinical Trial Academic Background Suicide prevention is a crucial topic in global public health, particularly in healthcare environments where identifying and intervening in suicide risks are top priorities. Traditional methods for identifying suicide risks rely mai...
Report on the Association Between Prenatal Exposure to Systemic Glucocorticoids and Offspring Mental Disorders Academic Background Glucocorticoids are widely used among pregnant women, particularly those at high risk of preterm birth or with autoimmune disorders. These treatments can reduce neonatal morbidity and mortality or alleviate symptoms by ...
A Systematic Review and Meta-Analysis of Glutamatergic Medications for Obsessive-Compulsive and Related Disorders (OCRDs) Academic Context Obsessive-Compulsive and Related Disorders (OCRDs) represent a group of neuropsychiatric conditions characterized by excessive, persistent obsessions or compulsions. These disorders include Obsessive-Compulsive ...
Academic Background Caregivers of patients with Primary Malignant Brain Tumors (PMBT) face significant psychological distress. PMBT is not only an incurable cancer but also accompanied by degenerative neurological conditions, leading caregivers to cope with the gradual loss of the patient’s physical functions and irreversible changes in personality...
Multimodal Neuroimaging Study of Structural and Functional Brain Alterations in Individuals with Opioid Use Disorder Academic Background Opioid Use Disorder (OUD) is a complex chronic condition that has multifaceted negative impacts on an individual’s life and is closely associated with an increased risk of mortality. In 2021, over 80,000 deaths in...
D1R-5-HT2AR Uncoupling Alleviates Depressive Behaviors Through HDAC Signaling Research Background Major depressive disorder (MDD) is a globally prevalent and life-threatening mental illness, closely associated with poor physical health. Despite the availability of various treatments, including medications and psychotherapy, many patients exhibit po...