Hypoxia- and Postirradiation Reoxygenation-Induced HMHA1/ARHGAP45 Expression Contributes to Cancer Cell Invasion in a HIF-Dependent Manner

Medicine, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
hypoxia   radiation   reoxygenation   cancer cell invasion   HIF-dependent   HMHA1   ARHGAP45  

Contribution of HMHA1/ARHGAP45 Expression Induced by Hypoxia and Post-Radiation Reoxygenation to Cancer Cell Invasion: An HIF-Dependent Mechanism Background and Motivation Prior studies have extensively demonstrated that cancer cells in solid tumors acquire malignant characteristics such as invasiveness and treatment resistance under hypoxic condit...