Minocycline Abrogates Individual Differences in Nerve Injury-Evoked Affective Disturbances in Male Rats and Prevents Associated Supraspinal Neuroinflammation

Medicine, Psychiatry, Neurology,
anhedonia   chronic constriction injury   depression-like behaviour   hippocampus   pain-related disability   radial arm maze  

Chronic Neuropathic Pain Affects Individual Emotional and Behavioral Disorders, Minocycline Shows Antidepressant Effect in Mouse Models Background Chronic Neuropathic Pain (CNP) has a profound impact on patients’ quality of life, but there are significant differences in individual responses to this pain. Some patients exhibit severe pain-related em...