Accelerating Ionizable Lipid Discovery for mRNA Delivery Using Machine Learning and Combinatorial Chemistry

Chemistry, Computational Chemistry, Information Science, Artificial Intelligence, Life Sciences, Biochemistry, Bioengineering,
mRNA delivery   machine learning   ionizable lipids   combinatorial chemistry   lipid nanoparticles  

Accelerating the Discovery of Ionizable Lipids for mRNA Delivery using Machine Learning and Combinatorial Chemistry Research Background To fully realize the potential of mRNA therapies, it is essential to expand the toolkit of lipid nanoparticles (LNPs). However, a key bottleneck in LNP development is identifying new ionizable lipids. Previous stud...