Demonstrated Efficacy and Mechanisms of Sensitivity of ONC201 in H3K27M-Mutant Diffuse Midline Glioma

Demonstrated Efficacy and Mechanisms of Sensitivity of ONC201 in H3K27M-Mutant Diffuse Midline Glioma

Medicine, Pediatrics, Neurology, Oncology,
ONC201   H3K27M-DMG   tumor treatment   mechanism study   clinical trial  

Review of Two New Studies on ONC201 Treatment for H3K27M-Mutant Diffuse Midline Glioma (H3K27M-DMG) This review reports on two new studies investigating the small molecule compound ONC201 for the treatment of H3K27M-mutant diffuse midline glioma (H3K27M-DMG). Background: H3K27M-DMG is an aggressive primary brain tumor that predominantly affects chi...