Structure-Activity Relationship Studies of ME1111, a Novel Antifungal Agent for Topical Treatment of Onychomycosis

Chemistry, Medicinal Chemistry, Medicine, Infectious Diseases, Pharmacy,
onychomycosis   antifungal agent   structure-activity relationship   topical treatment   ME1111   nail permeability   keratin binding  

Structure-Activity Relationship Studies of ME1111—A Novel Antifungal Agent for Topical Treatment of Onychomycosis Background Onychomycosis is a globally prevalent disease affecting approximately 5.5% of the world’s population. Among its subtypes, distal-lateral subungual onychomycosis (DLSO) is the most common. The treatment of onychomycosis typica...