Single-cell long-read sequencing-based mapping reveals specialized splicing patterns in developing and adult mouse and human brain

Medicine, Neurology, Life Sciences, Cell Biology, Biochemistry, Genetics,
splicing isoforms   splicing regulation   development   regions   cell types  

Single-cell sequencing technology reveals unique splicing patterns in developing and adult mouse and human brains In the nervous system, the splicing patterns of messenger RNA (mRNA) play a critical role in establishing cellular identity and regulating cellular functions. However, a comprehensive atlas depicting the mRNA splicing patterns across br...