A Quantitative Ultrastructural Timeline of Nuclear Autophagy Reveals a Role for Dynamin-like Protein 1 at the Nuclear Envelope

Life Sciences, Cell Biology,
nuclear autophagy   dynamin-like protein 1   nuclear envelope   ultrastructure   yeast   membrane fission   cellular homeostasis  

Background Introduction The nuclear envelope (NE) is a critical barrier between the nucleus and the cytoplasm, responsible for maintaining the stability of the nuclear environment. The integrity of the nuclear envelope is essential for normal cellular function, and its disruption is closely linked to aging and various diseases. Autophagy is a vital...

Plasma Membrane Damage Limits Replicative Lifespan in Yeast and Induces Premature Senescence in Human Fibroblasts

Medicine, Geriatrics, Life Sciences, Cell Biology, Biochemistry, Immunology,
plasma membrane damage   replicative lifespan   premature senescence   yeast   fibroblasts  

Scientific Research Report: Plasma Membrane Damage Limits Yeast Replicative Lifespan and Induces Premature Senescence in Human Fibroblasts Background and Research Motivation Plasma Membrane Damage (PMD) is a phenomenon experienced by all cell types in response to environmental disturbances and spontaneous cellular activities. Previous studies have ...