Academic Background As global population ageing intensifies, the impact of air pollution on public health becomes increasingly significant. Fine particulate matter (PM2.5) pollution is recognized as a major factor contributing to health issues such as cardiovascular diseases, chronic respiratory illnesses, and cognitive impairments. Particularly in...
Aging is one of the major risk factors for a variety of chronic diseases and death. However, chronological age does not fully reflect individual differences in the biological aging process. Phenotypic age is a composite score based on routine clinical markers, used to differentiate individuals within the same age group who have varying risks of dis...
ESICM Consensus: Management and Challenges of Very Old Patients in Critical Care Academic Background With the global aging population, the proportion of “very old patients” (aged 80 years and above) in intensive care units (ICUs) is rapidly increasing. This group is characterized by functional impairments and a high prevalence of complex multimorbi...
The Protective Role of Parenthood on Brain Function Academic Background Parenthood is a universal stage in human life that profoundly impacts both the body and mind, and may also have long-term effects on brain function. However, current research on the long-term impact of parenthood on brain function, especially its relationship with brain aging, ...
Brain Age Prediction Study Based on MEG Time Series Academic Background With the extension of human lifespan, understanding changes in the brain throughout the life cycle has become increasingly important. The structure and function of the brain undergo significant changes with age, which not only affect cognitive functions but are also closely rel...
Effects of Exogenous β-Hydroxybutyrate on BDNF Signaling, Cognition, and Amyloid Precursor Protein Processing in Humans with Type 2 Diabetes and Insulin-Resistant Rodents Academic Background Patients with type 2 diabetes (T2D) have a significantly increased risk of developing neurodegenerative diseases, such as Alzheimer’s disease (AD), later in li...
Research Report on Changes in the Metabolome of Senescent Myoblasts Research Background As age increases, the function of skeletal muscle gradually deteriorates, a phenomenon closely related to the senescence of muscle stem cells (satellite cells). Satellite cells play a key role in muscle injury repair. However, during the aging process, the funct...
The Impact of Robot Monitoring Behavior on Distraction and Technology Acceptance in Older Adults Academic Background With the intensification of societal aging, the demand for elderly care is increasing. Especially during the COVID-19 pandemic, psychological and physiological health issues faced by older adults due to social isolation have become m...
Promoting Healthy Longevity: Implementation Recommendations for the Hevolution Alliance for Aging Biomarkers Initiative Academic Background and Research Motivation With the intensification of global population aging, human life expectancy has significantly increased, but the growth in healthy life expectancy (i.e., years lived in good health) has b...
The Impact of Aging on Implicit Motor Learning and Short-term Memory: A Study Based on Force Field Adaptation Research Background Motor adaptation is the process by which the brain adjusts motor strategies in response to environmental changes, typically involving two mechanisms: explicit learning and implicit learning. Explicit learning is a rapid,...