The Impact of Cognitive Load on Interlimb Differences in Motor Control in Older Adults Academic Background In daily life, we often observe that the dominant hand (e.g., the right hand in right-handed individuals) performs better than the non-dominant hand in simple tasks. However, these interlimb differences may be influenced by task complexity and...
Research on Choroid Plexus Aging and Cerebrospinal Fluid Dynamics Background Introduction The choroid plexus (CHP) is a highly vascularized structure located within the brain ventricles, primarily responsible for the production of cerebrospinal fluid (CSF) and the clearance of metabolic waste. It plays a crucial role in maintaining neurofluid homeo...
Association Between Choroid Plexus Volume and Cognitive Function in Community-Dwelling Older Adults: A Research Study Academic Background With the increasing global aging population, the number of dementia patients is rising annually. Early identification of older adults with declining cognitive function and guiding them toward preventive and thera...
The functional decline of the immune system with aging is characterized by an increase in innate immune cells (e.g., granulocytes) and a decrease in adaptive immune cells (e.g., B cells). This imbalance in the immune system is closely related to the onset of various diseases, particularly myeloid leukemia and immune deficiencies common in the elder...
Academic Report on the Study “Exposure to School Racial Segregation and Late-Life Cognitive Outcomes” In recent years, the prevalence of Cognitive Impairment and Dementia among the elderly has been on the rise. In the U.S., significant disparities in cognitive health exist between non-Hispanic Black individuals and non-Hispanic White individuals. R...
Report on the Management of Chinese Older Adults with Type 2 Diabetes through Couple-Based Interventions: A Randomized Clinical Trial Academic Background Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic diseases globally, particularly common among older adults. China has the largest number of diabetes patients worldwide, reachin...
Comparative Analysis of Recombinant Quadrivalent Influenza Vaccine and Standard Egg-Based Quadrivalent Influenza Vaccine in Nursing Home Residents: A Cluster Randomized Trial Academic Background Influenza is among the primary respiratory pathogens causing morbidity and mortality among the elderly worldwide, particularly in nursing home residents wh...
Research Background Alzheimer’s Disease (AD) is a common neurodegenerative disorder characterized by the deposition of amyloid-beta (Aβ) plaques and abnormal phosphorylation of tau protein. Recent studies have increasingly highlighted the role of cerebrovascular alterations in the pathogenesis of AD. Specifically, endothelial cell damage and inflam...
Lithocholic Acid Phenocopies Anti-Ageing Effects of Caloric Restriction Academic Background Caloric restriction (CR) is a dietary intervention used to promote health and longevity by reducing food intake. Although CR has been shown to extend the lifespan of various organisms, the specific metabolic mechanisms behind its effects remain unclear. In p...
Stem Cell Transplantation Extends the Reproductive Lifespan of Naturally Aging Cynomolgus Monkeys Background of the Study The ovary is a crucial organ for female reproduction and health, responsible for producing oocytes and secreting sex hormones. As women age, ovarian reserves gradually decline, eventually leading to menopause, which brings about...