Synergistic Antitumor Activity by Dual Blockade of CCR1 and CXCR2 Expressed on Myeloid Cells within the Tumor Microenvironment

Synergistic Antitumor Activity by Dual Blockade of CCR1 and CXCR2 Expressed on Myeloid Cells within the Tumor Microenvironment

Medicine, Medical Laboratory Science, Gastroenterology, Oncology, Life Sciences, Biochemistry, Immunology,
CCR1   CXCR2   Colorectal Cancer   Tumor Microenvironment   Dual Blockade   Myeloid Cells   Antitumor Activity  

Achieving Synergistic Antitumor Activity by Dual Blocking of CCR1 and CXCR2 Expression in Myeloid Cells Background Introduction Colorectal Cancer (CRC) poses a global health crisis, with its incidence and mortality rates rapidly rising in recent years. Over the past 15 years, the mortality rate of CRC has increased by more than 30%, and it is expec...