Original Title: 《Associations of CSF BACE1 with Amyloid Pathology, Neurodegeneration, and Cognition in Alzheimer’s Disease》 Background and Research Purpose Alzheimer’s Disease (AD) is a leading cause of dementia in the elderly, characterized by the accumulation of β-amyloid protein (Aβ) plaques in the brain. Beta-site APP cleaving enzyme 1 (BACE1) ...