Structure-Guided Development of Selective Caseinolytic Protease P Agonists as Antistaphylococcal Agents

Chemistry, Medicinal Chemistry, Medicine, Infectious Diseases, Pharmacy, Life Sciences, Biochemistry, Microbiology,
Caseinolytic Protease P   Antistaphylococcal Agents   ZG297   MRSA   Structure-Guided Design   Selective Agonists   Antibiotics  

Structure-Guided Development of Selective Caseinolytic Protease P Agonists as Antistaphylococcal Agents Academic Background Staphylococcus aureus is a common Gram-positive pathogen that can cause various human infections, including skin and soft tissue infections. With the widespread dissemination of methicillin-resistant Staphylococcus aureus (MRS...