Inflammatory Bowel Disease (IBD) is a chronic inflammatory condition that primarily includes Ulcerative Colitis (UC) and Crohn’s Disease (CD). The incidence of IBD has been increasing globally, imposing significant health and economic burdens on patients and society. Currently, the diagnosis of IBD relies mainly on endoscopy, but this method is exp...
In recent years, the significant role of the human gut microbiota (HGM) in the metabolism of drugs and nutrients has gradually been recognized. The gut microbiota not only affects the bioavailability of orally administered drugs but also participates in the biotransformation of drugs and bioactive molecules through its metabolic enzymes, thereby in...
Iodine (I) is a trace element of significant importance to human health and the environment. It is a major component of human thyroid hormones, such as thyroxine (T4) and triiodothyronine (T3), directly influencing thyroid function. However, approximately 1.9 billion people worldwide are affected by Iodine Deficiency Disorder (IDD), with symptoms i...
Flatulence is a common occurrence in daily life, often resulting from the fermentation of undigested food components by the gut microbiota. While flatulence is generally harmless, it can lead to discomfort, bloating, and even chronic conditions such as irritable bowel syndrome (IBS). Certain foods, particularly those rich in dietary fiber like bean...
In recent years, the role of gut microbiota in health and disease has garnered widespread attention. Research indicates that the diversity and composition of gut microbiota are closely related to the development and progression of cardiovascular disease (CVD). CVD is one of the leading causes of death globally, and inflammation plays a significant ...
The Key Role of Human Milk Microbes and Oligosaccharides in Infant Gut Microbiota Development Academic Background The development of infant gut microbiota is crucial in early life, and breastfeeding is one of the key drivers of this process. Human milk not only provides essential nutrients for infants but also contains a rich array of microbes and ...
Iron is one of the most abundant elements on Earth, widely present in the Earth’s crust, water bodies, and living organisms. The redox reactions of iron in natural cycles, especially in water bodies, play a crucial role in nutrient cycling and pollutant degradation in ecosystems. However, the mechanisms of iron cycling and its interaction with micr...
In recent years, the role of the gut microbiome in human health and disease has garnered significant attention. Research indicates that gut microbial dysbiosis is closely associated with various chronic diseases, such as obesity, inflammatory bowel disease, cancer, and neurodegenerative disorders. Diet, as a critical factor influencing the gut micr...
Uranium (U) is a radioactive element widely present in the environment, primarily existing in its hexavalent (U(VI)) and tetravalent (U(IV)) oxidation states. Under oxidizing conditions, U(VI) is the dominant stable form, while under reducing conditions, U(VI) can be reduced to U(IV). This reduction process can occur through abiotic pathways (e.g.,...
Selenium (Selenium) is an essential trace element widely found in nature and involved in various biological metabolic processes. However, when selenium concentrations are too high, they can cause severe toxic effects on humans, animals, and the environment. Industrial activities, especially coal combustion in coal-fired power plants, are one of the...