Relaxation-Exchange Magnetic Resonance Imaging (REXI): A Non-Invasive Imaging Method for Evaluating Trans-Barrier Water Exchange in the Choroid Plexus

Non-Invasive Imaging Technique for Evaluating Trans-Barrier Water Exchange in the Choroid Plexus Background Introduction The choroid plexus (CP) is a critical site for cerebrospinal fluid (CSF) production and an essential component of the blood-cerebrospinal fluid barrier (BCSFB). The CP regulates CSF secretion and absorption, maintaining brain hom...

Multiplex Cerebrospinal Fluid Proteomics Identifies Biomarkers for Diagnosis and Prediction of Alzheimer's Disease

Cerebrospinal Fluid Proteomics Study for Diagnosis and Prediction of Alzheimer’s Disease Background and Research Objectives Alzheimer’s disease (AD) is a neurodegenerative disease that leads to memory loss and cognitive decline, and currently, there is no effective cure globally. Traditionally, the pathological features of AD include β-amyloid (Aβ)...