Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling

Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling

Medicine, Rheumatology and Immunology, Oncology, Life Sciences, Immunology,
CAR T cells   Diffuse large B cell lymphoma   Single-cell analysis   Cell function   Clinical response  

Utilizing Dynamic Single-Cell Analysis to Discover a Clinically Effective Chimeric Antigen Receptor T-Cell Subset for Treating Diffuse Large B-Cell Lymphoma Research Background Chimeric antigen receptor (CAR) T-cell therapy has been proven to be an effective treatment for B-cell malignancies. However, it remains challenging to predict individual cl...