The Microbial Metabolite Agmatine Acts as an FXR Agonist to Promote Polycystic Ovary Syndrome in Female Mice

Medicine, Obstetrics and Gynecology, Endocrinology, Gastroenterology, Life Sciences, Biochemistry, Microbiology,
Polycystic Ovary Syndrome   Agmatine   FXR   Gut Microbiome   Hormones   Insulin Resistance  

Microbial Metabolite Ethylamine as FXR Agonist Promotes Polycystic Ovary Syndrome in Female Mice I. Research Background and Objectives Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder affecting 6%-20% of women of reproductive age worldwide. Symptoms of PCOS include hyperandrogenemia, ovarian dysfunction, and polycystic ...