Metabolism of Primary High-Grade Serous Ovarian Carcinoma (HGSOC) Cells under Limited Glutamine or Glucose Availability

Medicine, Obstetrics and Gynecology, Oncology,
High-Grade Serous Ovarian Carcinoma   Metabolic Flexibility   Oxidative Phosphorylation   Endoplasmic Reticulum Stress   Chemotherapy Resistance  

Metabolism of High-Grade Serous Ovarian Carcinoma (HGSOC) Cells Academic Background High-Grade Serous Ovarian Carcinoma (HGSOC) is the most common and aggressive subtype of epithelial ovarian cancer. Most patients are diagnosed at stage III or IV, with a 5-year survival rate ranging from 20% to 40%. Treatment for HGSOC typically involves surgical r...