Spatiotemporal Imprinting of Tissue-Resident Memory CD8 T Cell Diversity

Spatiotemporal Imprinting of Tissue-Resident Memory CD8 T Cell Diversity Background Tissue-resident memory CD8 T cells (TRM cells) provide long-term immune protection at barrier sites such as the intestine. However, the heterogeneity of TRM cells and the mechanisms underlying their formation remain incompletely understood. Previous studies have ide...

Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule

Role of GLP-1R in T Cells and Its Regulatory Mechanism for Anti-transplant Immunity and Anti-tumor Immunity Academic Background Glucagon-like peptide-1 receptor (GLP-1R) is known as a key regulator of glucose metabolism, primarily expressed in pancreatic β cells. Previous studies have clarified that GLP-1R agonists have significant effects in reduc...