Isorhamnetin Ameliorates Dopaminergic Neuronal Damage via Targeting FOSL1 to Activate AKT/mTOR in 6-OHDA-Induced SH-SY5Y Cells

Medicine, Neurology, Life Sciences,
Isorhamnetin   FOSL1   AKT/mTOR pathway   6-OHDA   Parkinson's disease   oxidative stress   apoptosis  

Isorhamnetin Ameliorates 6-OHDA-Induced SH-SY5Y Cell Damage by Targeting FosL1 to Activate the Akt/mTOR Pathway Academic Background Parkinson’s Disease (PD) is a chronic neurodegenerative disorder characterized by the loss of dopaminergic neurons in the Substantia Nigra Pars Compacta (SNpc). This neuronal loss is closely associated with mitochondri...