TDO2 Inhibition Counters Benzo[a]pyrene-Induced Immune Evasion and Suppresses Tumorigenesis in Lung Adenocarcinoma

The Role of TDO2 Inhibition in Lung Cancer Immune Evasion Background Introduction Lung cancer is one of the leading causes of cancer-related deaths worldwide, with smoking recognized as a primary cause of its occurrence. Cigarette smoke contains numerous carcinogens, among which benzo[a]pyrene (BAP), a polycyclic aromatic hydrocarbon, has been show...

The N6-Methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma

The N6-Methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma

The Epitranscriptomic Landscape of N6-Methyladenosine Modification in Lung Adenocarcinoma Background Lung cancer is one of the most common cancers globally and a leading cause of cancer-related deaths. Non-small cell lung cancer (NSCLC) accounts for about 80%-85% of all lung cancer cases, among which lung adenocarcinoma (LUAD) is of particular conc...