Acetyl-CoA Metabolism Maintains Histone Acetylation for Syncytialization of Human Placental Trophoblast Stem Cells

Medicine, Obstetrics and Gynecology, Life Sciences, Cell Biology, Biochemistry,
Acetyl-CoA   Histone Acetylation   Human Placenta   Trophoblast Stem Cells   Metabolic Regulation  

The Role of Acetyl-CoA Metabolism in Maintaining the Synchronization of Human Trophoblast Stem Cells Research Background and Purpose The placenta is a crucial metabolic bridge between the mother and fetus during pregnancy, and its normal function is vital for the health of both. The placenta constantly differentiates through human trophoblast stem ...

Inhibition of Fatty Acid Uptake by TGR5 Prevents Diabetic Cardiomyopathy

Medicine, Endocrinology, Cardiovascular System, Life Sciences, Biochemistry,
Diabetic Cardiomyopathy   Fatty Acid Uptake   TGR5   Lipid Metabolism   Cardioprotection   Fatty Acid Transport   Metabolic Regulation  

Preventing Diabetic Cardiomyopathy through Suppressing TGR5-Mediated Fatty Acid Uptake Background and Problem Statement Diabetic Cardiomyopathy (DBCM) is a severe complication frequently faced by diabetic patients, characterized by lipid accumulation in the myocardium and cardiac dysfunction. Bile acid metabolism plays a crucial role in cardiovascu...