A Microbial Metabolite Inhibits the HIF-2α-Ceramide Pathway to Mediate the Beneficial Effects of Time-Restricted Feeding on MASH

Medicine, Hepatobiliary System, Basic Medical Sciences, Life Sciences, Biochemistry, Microbiology,
Microbial Metabolite   Time-Restricted Feeding   HIF-2α   Ceramide   MASH   MASLD   Ruminococcus Torques  

A Microbial Metabolite Mediates the Beneficial Effects of Time-Restricted Feeding on MASH by Inhibiting the HIF-2A-Ceramide Pathway Introduction Background: Metabolic Dysfunction-Associated Steatotic Liver Disease/Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH) is a major health problem affecting a quarter of the global population. MA...