SMARCA4 is a Haploinsufficient B Cell Lymphoma Tumor Suppressor that Fine-Tunes Centrocyte Cell Fate Decisions

Scientific Report: Study Reveals the Role of SMARCA4 in B Cell Lymphoma Background Introduction The germinal center (GC) plays a crucial role in the maturation and apoptosis of B cells. The GC reaction is a rapid and transient immune response structure that improves the affinity of B cells to specific antigens through somatic mutation and affinity ...