Tissue Factor Promotes TREX1 Protein Stability to Evade cGAS-STING Innate Immune Response in Pancreatic Ductal Adenocarcinoma

Medicine, Pharmacy, Oncology, Life Sciences, Immunology,
Pancreatic Ductal Adenocarcinoma   Tissue Factor   TREX1 Protein   cGAS-STING Pathway   Immune Evasion   Tumor Microenvironment   Targeted Therapy  

Tissue Factor Promotes TREX1 Protein Stability to Evade cGAS-STING Innate Immune Response in Pancreatic Ductal Adenocarcinoma Academic Background Pancreatic ductal adenocarcinoma (PDAC) remains one of the most challenging malignancies worldwide, with increasing incidence and mortality rates, particularly in advanced stages. Despite significant prog...