Complete Inhibition of Liver Acetyl-CoA Carboxylase Activity Exacerbates Liver Tumorigenesis in Mice Treated with Diethylnitrosamine

Medicine, Hepatobiliary System, Oncology, Life Sciences, Biochemistry,
liver cancer   de novo lipogenesis   acetyl-CoA carboxylase   tumorigenesis   diethylnitrosamine   metabolic pathway   mouse model  

Inhibition of Liver Acetyl-CoA Carboxylase (ACC) Activity Exacerbates Liver Tumorigenesis in Mice Academic Background Liver cancer is the sixth most common cancer globally and the third leading cause of cancer-related mortality. Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. In recent years, the burden of liver canc...