Natural Killer Cells Promote Neutrophil Extracellular Traps and Restrain Macular Degeneration in Mice

Medicine, Basic Medical Sciences, Ophthalmology, Life Sciences, Cell Biology, Biochemistry, Immunology,
natural killer cells   neutrophil extracellular traps   macular degeneration   mouse model   immune mechanisms  

Study on Macular Degeneration Reveals Inhibitory Effect of Natural Killer Cells on Disease Progression Background Age-related Macular Degeneration (AMD) is the leading cause of irreversible blindness among the elderly globally. With an aging population, the incidence of AMD is significantly increasing. Early features of AMD include the accumulation...

Piplartine Attenuates Aminoglycoside-Induced TRPV1 Activity and Protects from Hearing Loss in Mice

Chemistry, Medicinal Chemistry, Medicine, Neurology, Pharmacy, Life Sciences, Biochemistry,
hearing loss   aminoglycosides   TRPV1   mouse model   protective mechanism  

Piplartine Attenuates Aminoglycoside-Induced TRPV1 Activity and Protects from Hearing Loss in Mice Academic Background Hearing loss is a serious global health problem affecting over 400 million people worldwide, according to the World Health Organization. Aminoglycoside antibiotics, while widely used in medicine due to their broad-spectrum antibact...

Clonal Lineage Tracing with Recordable Barcodes Reveals Migration Histories of Metastatic Prostate Cancer

Medicine, Geriatrics, Urology, Oncology,
clonal lineage tracing   metastatic prostate cancer   barcodes   tumor evolution   mouse model   tumor heterogeneity  

title: “Utilizing Clonal Lineage Tracing with Recordable Barcodes Unveils the Migration History of Prostate Cancer Metastasis” author: Ryan N. Serio, Armin Scheben, *Billy Lu, *Domenic V. Gargiulo, Lucrezia Patruno, Caroline L. Buckholtz, Ryan J. Chaffee, Megan C. Jibilian, Steven G. Persaud, Stephen J. Staklinski, Rebecca Hassett, Lise M. Brault, ...