A Novel Method to Study CSF Flow and BOLD Coupling Using Real-Time Phase Contrast Interleaved with Cortical BOLD MRI

Medicine, Neurology, Medical Imaging, Life Sciences, Biophysics,
CSF flow   real-time phase contrast   BOLD   glymphatic system   brain clearance   BOLD-CSF coupling  

New Method for Studying the Coupling Between Cerebrospinal Fluid Flow and Cortical BOLD Signals Academic Background In recent years, the role of cerebrospinal fluid (CSF) in brain waste clearance has garnered significant attention. Traditionally, CSF was thought to primarily serve as a cushion and provide immune surveillance. However, growing evide...

Brief Communication: Brain Clearance is Reduced During Sleep and Anesthesia

Medicine, Neurology,
sleep   brain clearance   neuroscience  

Brain Clearance Mechanism Suppressed During Sleep and Anesthesia Background Clearing metabolic wastes and toxic substances from the brain is a crucial process for maintaining a healthy nervous system. However, the specific mechanism of this process has been debated. A widely discussed viewpoint suggests that the sleep state promotes the function of...