The Role of Motor Cortex in Striatal Motor Dynamics and Execution of Skilled and Unskilled Actions

Medicine, Basic Medical Sciences, Neurology, Life Sciences, Cell Biology,
motor cortex   striatal dynamics   action execution   neuroscience   lesions  

Exploring the Crucial Role of the Motor Cortex in Basal Ganglia and Dynamic Motor Control Research Background and Motivation The role of the motor cortex (Motor Cortex, M1) in motor generation and regulation has long been a significant topic in neuroscience. The interaction between M1 and the striatum in selecting and executing goal-directed action...

Application of Gene Therapy in Focal Cortical Dysplasia

Medicine, Neurology, Neurosurgery, Life Sciences, Genetics,
gene therapy   focal cortical dysplasia   epilepsy   neuroscience   behavioral disorder  

New Gene Therapy Approach May Control Epileptic Seizures Caused by Focal Cortical Dysplasia Focal Cortical Dysplasia (FCD) is a type of disorder caused by abnormal cortical development, often accompanied by drug-resistant epilepsy and cognitive and behavioral disorders. According to the classification criteria proposed by Najm et al. in 2022 for th...

brainlife.io: a decentralized and open-source cloud platform to support neuroscience research

Information Science, Computer Science, Medicine, Neurology,
neuroscience   neuroimaging   data standardization   data management   reproducibility   scientific utility  

Academic report: brainlife.io: A decentralized and open-source cloud platform supporting neuroscience research Background and Motivation Neuroscience research is rapidly developing, and the advancement of data standardization, management, and processing tools has made research more rigorous and transparent. However, this also brings about complex d...

A prognostic neural epigenetic signature in high-grade glioma

Medicine, Neurology, Neurosurgery, Oncology, Life Sciences, Cell Biology, Biochemistry,
glioma   neural epigenetics   prognostic signature   tumor biology   neuroscience  

Study of Neuroepithelial Genetic Markers and Prognosis in High-Grade Gliomas Background and Research Motivation High-grade gliomas are highly malignant brain tumors with generally poor patient prognosis. Previous preclinical model studies have suggested that interactions between neural and tumor cells drive tumor growth, but clinical validation of ...

Reactivation strength during cued recall is modulated by graph distance within cognitive maps

Medicine, Neurology, Clinical Psychology, Life Sciences, Biophysics,
reactivation   memory recall   cognitive maps   graph distance   magnetoencephalography   neuroscience   memory mechanisms  

Reactivation Strength in Memory is Modulated by Graph Distance in Cognitive Maps Research Background Memory formation and retrieval are among the crucial areas of research in neuroscience. Classic memory theories propose that memory depends on three distinct stages: encoding, consolidation, and retrieval. New episodic memories are formed through en...

Brief Communication: Brain Clearance is Reduced During Sleep and Anesthesia

Medicine, Neurology,
sleep   brain clearance   neuroscience  

Brain Clearance Mechanism Suppressed During Sleep and Anesthesia Background Clearing metabolic wastes and toxic substances from the brain is a crucial process for maintaining a healthy nervous system. However, the specific mechanism of this process has been debated. A widely discussed viewpoint suggests that the sleep state promotes the function of...