New Gene Therapy Approach May Control Epileptic Seizures Caused by Focal Cortical Dysplasia Focal Cortical Dysplasia (FCD) is a type of disorder caused by abnormal cortical development, often accompanied by drug-resistant epilepsy and cognitive and behavioral disorders. According to the classification criteria proposed by Najm et al. in 2022 for th...

Academic report: brainlife.io: A decentralized and open-source cloud platform supporting neuroscience research Background and Motivation Neuroscience research is rapidly developing, and the advancement of data standardization, management, and processing tools has made research more rigorous and transparent. However, this also brings about complex d...

Study of Neuroepithelial Genetic Markers and Prognosis in High-Grade Gliomas Background and Research Motivation High-grade gliomas are highly malignant brain tumors with generally poor patient prognosis. Previous preclinical model studies have suggested that interactions between neural and tumor cells drive tumor growth, but clinical validation of ...

Reactivation Strength in Memory is Modulated by Graph Distance in Cognitive Maps Research Background Memory formation and retrieval are among the crucial areas of research in neuroscience. Classic memory theories propose that memory depends on three distinct stages: encoding, consolidation, and retrieval. New episodic memories are formed through en...

Brain Clearance Mechanism Suppressed During Sleep and Anesthesia Background Clearing metabolic wastes and toxic substances from the brain is a crucial process for maintaining a healthy nervous system. However, the specific mechanism of this process has been debated. A widely discussed viewpoint suggests that the sleep state promotes the function of...