Modeling the Atrioventricular Conduction Axis using Human Pluripotent Stem Cell-Derived Cardiac Assembloids

Modeling the Atrioventricular Conduction Axis Based on Human Pluripotent Stem Cell-Derived Cardiac Assembloids Research Background The atrioventricular (AV) conduction axis is responsible for electrical conduction between the atrium and the ventricle and is a core component of the cardiac electrophysiological system. The delay function of AV conduc...

A Primate-Specific Endogenous Retroviral Envelope Protein Sequesters SFRP2 to Regulate Human Cardiomyocyte Development

A Primate-Specific Endogenous Retroviral Envelope Protein Regulates Human Cardiomyocyte Development by Inhibiting SFRP2 Research Background and Significance Endogenous Retroviruses (ERVs) are remnants of ancient viral infections that integrated into the host genome and were inherited through the germline to modern human genomes during evolution. Th...