In Vitro Model of Vertebrate Trunk Development Academic Background The development of the vertebrate trunk is a highly coordinated process involving the generation and organization of multiple cell types. At the core of this process are progenitor cells located in the posterior of the embryo, which differentiate into tissues such as the neural tube...

A Primate-Specific Endogenous Retroviral Envelope Protein Regulates Human Cardiomyocyte Development by Inhibiting SFRP2 Research Background and Significance Endogenous Retroviruses (ERVs) are remnants of ancient viral infections that integrated into the host genome and were inherited through the germline to modern human genomes during evolution. Th...

Exploring XIST Silencing and Repressor Factors on the X Chromosome in Early Human and Bovine Embryos Research Background X chromosome inactivation is a dosage compensation mechanism in mammals, aimed at balancing the expression of X-linked genes between females and males. The XIST gene locus can trigger transcriptional silencing of the additional X...